Journal: International Journal of Oral Science

Article Title: Cetylpyridinium chloride mouth rinses alleviate experimental gingivitis by inhibiting dental plaque maturation

doi: 10.1038/ijos.2016.18

Figure Lengend Snippet: Gingival health changes across experimental gingivitis study with or without CPC mouth rinse treatment. Boxes represent the interquartile range (IQR), and the lines inside represent the median. Whiskers denote the lowest and highest values within 1.5 × IQR. Before Day 0, all subjects had received a rigorous oral hygiene regimen for 3 weeks, which resulted in greatly reduced MGI and BOP (median MGI and BOP were 1.02 and 1.00, respectively; “Baseline”) that corresponded to a healthy gum state. Then, the subjects further underwent an oral hygiene programme with and without CPC treatment for 3 weeks. In the control group, significantly increased BOP (mean 26.00±1.36) and MGI (mean 2.12±0.07) were observed compared with Baseline, whereas in the CPC group, slightly increased BOP (mean 13.17±0.99) and MGI (mean 1.53±0.04) were found. BOP, bleeding on probing; CPC, cetylpyridinium chloride; MGI, mazza gingival index.

Article Snippet: Within-subject temporal dynamics of plaque microbiota and clinical symptoms of gingivitis were profiled via 16S ribosomal RNA (rRNA) gene pyrosequencing and assessment via the Mazza gingival index (MGI).

Techniques: Control

Journal: International Journal of Oral Science

Article Title: Cetylpyridinium chloride mouth rinses alleviate experimental gingivitis by inhibiting dental plaque maturation

doi: 10.1038/ijos.2016.18

Figure Lengend Snippet: Distinct temporal dynamics of 25 taxa from Baseline to Day 21 between the CPC and control groups. ( a ) Between-treatment comparisons of bacterial abundance at each time point. The abundance change for each taxon was calculated as the abundance at Day 21 deducted from that at baseline. ( b ) The temporal changes in relative abundance for these 25 taxa were significantly (adjusted P <0.05, Wilcoxon rank-sum test) different between subjects in the CPC and control group. The dots were classified into three groups: red, gingivitis enriched; green, gingivitis depleted; blue, neutral. Bacterial classification was based on comparing the microbial profiles of the control group at Baseline and Day 21. CPC, cetylpyridinium chloride.

Article Snippet: Within-subject temporal dynamics of plaque microbiota and clinical symptoms of gingivitis were profiled via 16S ribosomal RNA (rRNA) gene pyrosequencing and assessment via the Mazza gingival index (MGI).

Techniques: Control

Journal: International Journal of Oral Science

Article Title: Cetylpyridinium chloride mouth rinses alleviate experimental gingivitis by inhibiting dental plaque maturation

doi: 10.1038/ijos.2016.18

Figure Lengend Snippet: Co-occurrence and co-exclusion relationships of oral bacteria in the two treatments. Genus-level correlation networks were displayed for the control group and the CPC group at Day 21. Each node represents a bacterial genus, and each edge represents a significant co-occurrence (solid line)/co-exclusion (dotted line) relationship. Line thickness is proportional to the degree of correlation (Spearman's ρ ). The nodes were classified into three groups: red, gingivitis enriched; green, gingivitis depleted; blue, neutral. CPC, cetylpyridinium chloride.

Article Snippet: Within-subject temporal dynamics of plaque microbiota and clinical symptoms of gingivitis were profiled via 16S ribosomal RNA (rRNA) gene pyrosequencing and assessment via the Mazza gingival index (MGI).

Techniques: Bacteria, Control